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Researchers in America have discovered the cause of age related stomach fat. The study of ‘City of Hope’ found that new adult stem cells increase fat around the stomach.
Know, why the waist becomes wide by reaching the middle of age. (Canva)
Highlights
- American researchers discovered the cause of age related stomach fat.
- New adult stem cells increase fat around the abdomen.
- Research can develop treatment to prevent abdominal fat in future.
A team of researchers from America has detected the cause of age related stomach fat, which helps to understand why our back becomes wide by reaching the middle of age. This research has been published in the science journal, and its findings are expecting that new treatment methods may develop to prevent stomach fat and increase healthy lifespan in future. This research has been done by ‘City of Hope’.
Arthur Rigs Diabetes and Metabolism Research Institute of the City of Hope, at the Molecular and Cellular Endocrinology Associate Professor Kiong (Anabel) Wang, said, “People lose muscles with aging and increase the fat in the body, even if they live the same.” He added, “We found that a new type of adult stem cells come into the body with aging and accelerate the production of new fat cells around the stomach.”
First confirmed on human cells on mice
-Wang and his team, along with UCLA lab co-author Shia Yang, experimented on mice, which were later confirmed on human cells. Researchers focused on the White Edipose Tissue (WAT), which is the fat tissue responsible for age -related weight gain. Although it is known that fat cells get large with age, researchers suspected that WAT also produces new fat cells, which means that there could be no limit to its growth.
– To test their estimate, researchers focus on adipocyte projector cells (APCS), which are a type of stem cells found in WAT, which turn into fat cells. The team first took APCS from young and old mice and transplanted them to young mice of another group. The APCS extracted from old mice created a lot of new fat cells.
– When the team transplanted APCS from young mice into old mice, these stem cells did not create much new fat cells. These results prove that the old APCS itself has the ability to create new fat cells. This conclusion shows that it is very important to control the construction of new fat cells to deal with age related obesity.
